Francisco de Espinosa was listed on the 1540 muster as a footman. The only other certain reference to him is in the report of Juan Jaramillo in which it is said that "Espinosa" died from eating a poisonous plant somewhere near Chichilticale in southeastern Arizona.
?Mier y Terán Rocha, La primera traza, II:529: [a Francisco de Espinosa received the grant from the cabildo of México of a solar in January 1527 within the traza next to Antón Bravo and near Pedro de Nájera [the least likely, because no known connection to any members]
?AGI, Pasajeros, L.2, E.5294 [Oct. 9, 1538, son of Juan de Espinosa and Ana de Vera, in the armada of Pedro de Alvarado]
?AGI, Pasajeros, L.2, E.363 [Mar. 24, 1535, son of Juan de Coca and Francisca Velázquez, vecinos of Segovia, to Cartagena w/Junco (Junco went to Santa Marta)]
1540, Feb: Muster in Flint & Flint, Documents, Document 12 [footman, arcabuz, native arms]
Jaramillo in Flint & Flint, Documents, Document 30 [2r: a Spaniard called Espinosa and two other persons died from poisonous herbs]
?Piferrer, Nobiliario, 4:148-149, #1755 [progenitor was Sancho de Espinosa, mayordomo of the conde de Castilla don Sancho; Diego García de Espinosa was the montero of the camara of SM; came from Espinosa de los Monteros, natives of the concejo of Barruezo, barrio of Gallemo, known by the name of solar de Espinosa; Dantiago of Espinosa Rui-Diáz was grandson of Diego];
?Himmerich, Encomenderos [Francisco de Ribadeo: married Leonor Osorio of Sevilla, widow of Basque conqueror Juan de Espinosa, AGI, Pasajeros, L.1, E.250: 1511, native of Mazariegos: Palencia, son of Juan de la Linde and María Sánchez, #1520, 1513, Hernán Brusa and Mari Sánchez de Espinosa, Espinosa de los Montero (Burgos), #1642, 1513, Diego Hernández Cornejo came with Juan de Espinosa, son of Juan de Espinosa]